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Electrophysiological whole-cell voltage- and current-clamp recordings in horizontal or coronal brainstem slices has revealed a rapid leptin-induced depolarization of these NTS GCG + neurons, thus confirming the ability of leptin to directly stimulate central GLP-1 secretion [351]
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Typical Maintenance Dose Ranges Semaglutide (Ozempic/Wegovy)0.25 - 1.0 mg/week Tirzepatide (Mounjaro/Zepbound)2.5 - 5.0 mg/week Compounded versionsFlexible - provider-determined The advantage of compounded semaglutide or tirzepatide is dosing flexibility
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